The ides is to allow the subscriber to opt out of emails from a specific sequence or a specific segment of your list/interest. Instead of losing that subscriber altogether, you can just slice that subscriber from a particular segment.
Unsubscribe Subscribers Based on Interests
Keep Your Email List Healthy, Happy, & Fresh
Key Component of this Unsubscribing Approach
How to Create a Rule in ConvertKit
How to Create an Unsubscribe Page